Detalhe da pesquisa
1.
Extracellular HSP90 promotes differentiation of lens epithelial cells to fiber cells by activating LRP1-YAP-PROX1 axis.
FASEB J;
37(2): e22783, 2023 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36705056
2.
Crosstalk between heat shock factor 1 and signal transducer and activator of transcription 3 mediated by interleukin-8 autocrine signaling maintains the cancer stem cell phenotype in liver cancer.
J Gastroenterol Hepatol;
38(1): 138-152, 2023 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36300571
3.
Targeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective.
Med Res Rev;
42(4): 1607-1660, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35312190
4.
Discovery of Unique Bis-Substituted Aromatic Amide Derivatives as Novel Highly Potent Antibiotics for Combating Methicillin-Resistant Staphylococcus aureus (MRSA).
J Med Chem;
67(3): 2129-2151, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38289145
5.
Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
Int J Biol Sci;
20(2): 486-501, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38169532
6.
Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy.
Eur J Med Chem;
261: 115792, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37690265
7.
A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia.
Biomed Pharmacother;
166: 115358, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37634473
8.
B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell Lymphomas.
J Med Chem;
65(23): 15559-15583, 2022 12 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36441945
9.
An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo.
Cancer Lett;
529: 100-111, 2022 03 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34990752
10.
Biotin attenuates heat shock factor 4b transcriptional activity by lysine 444 biotinylation.
Biochem Biophys Rep;
30: 101227, 2022 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35198740
11.
Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane.
Eur J Med Chem;
190: 112141, 2020 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32078862
12.
Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression.
Adv Sci (Weinh);
7(9): 1903483, 2020 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32382484
13.
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.
J Med Chem;
63(2): 676-695, 2020 01 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31895575
14.
Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin.
J Med Chem;
62(10): 4949-4966, 2019 05 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31026162
15.
Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents.
Eur J Med Chem;
162: 203-211, 2019 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30447433
16.
Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.
Eur J Med Chem;
96: 269-80, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25899332
17.
Corrigendum to "Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents" [Eur. J. Med. Chem. 162 (162) (2019) 203-211].
Eur J Med Chem;
168: 385, 2019 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30826513